Hi, If your wife is experiencing irregular periods and has a history of polycystic ovary syndrome (PCOS), it is important to seek medical attention as soon as possible to determine the underlying cause of her symptoms and receive appropriate treatment. One possible treatment option for PCOS-related irregular periods is hormonal birth control, which can help regulate the menstrual cycle and reduce symptoms such as acne and facial hair growth. Other treatment options may include medications to help regulate insulin levels, which can be elevated in women with PCOS, or fertility medications to help with ovulation and conception. It is also important to maintain a healthy lifestyle, including regular exercise and a balanced diet, to support overall health and well-being. Your wife should work closely with her healthcare provider to develop a personalized treatment plan based on her individual needs and medical history. If your wife is experiencing prolonged or heavy bleeding or other concerning symptoms, it is important to seek medical attention right away. Her healthcare provider can perform a physical exam, order diagnostic tests such as blood work or imaging studies, and provide appropriate treatment based on her individual needs and medical history. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Priyanka, General & Family Physician