It all started around 29.12.2013g., When he had flu symptoms and slightly increased temepature and after taking Analgin get intense itching all over the body saying that it his blood itches and not skin We thought it was allergies and the doctor advised us to beat Methylprednisolone 40mg. Then take antihistamines. On 31.03.2014g. itching intensified again in its emergency center would again Methylprednisolone 40mg. Then everything faded. On 20.05.2014g. - Get intense itching all over the body again and again we thought it was allergies and the doctor advised us to beat Methylprednisolone 40mg. (About 20 hours) Ease it a bit, but after two hours the itching started again. Then I would still 1 Methylprednisolone 40mg (about 22 hours); He took antihistamines again. On 23/05/2014 Dermatologist expression - Diprofos - 1 injection and Methylprednisolone 40 mg - x 1 a day for two days. By 27.05.2014g. But the itching did not stop and louder evening. Visit an allergist and dermatologist. Allergist said that certainly is not allergy and carry out tests on Biliurubin and ultrasound gastroenterologist at .. (research of 05.27.2014). Gastroenterologist said that everything is wrong with the liver and kidneys and there is no obstruction of bile ducts. I can not implement it because it is under doctor now. They sent him to the infectious and from there said that it was not out there again and go to a gastroenterologist - so 3 times. Discharged: Transmetil (ADEMETIONINE), Hepa SAVE, Vitamin E, Vitamin B complex and Ursofalk (ursodeoxycholic acid) for treatment, but symptoms decreased to 03.06.2014g. Ultimately 03.06.2014g. accepted for treatment in Infectious Disease treated with it: - Transmetil (ADEMETIONINE) - Ursofalk (ursodeoxycholic acid) 250mg (1 morning, noon and night x2) - Glucose - Vitamine C - Hepamerts (- L and ornithine - L aspartate 3 g. Granules, oral solution) 3x1 They said that treatment for hepatitis. It turned out that itching is elevated Biliurubin. At their research on 03,06,2014 found that ASAT, ALAT, GGTP improve. There was no hepatitis, according to research. Doctors have sameniya for: - Hepatitis A, B, C, E - Toxic hepatitis - Mononucleosis All tests for viruses / parasites, etc. were negative apply epicrisis After adopting again in Sveta Marina - Varna, Gastroenterology - things faded away and fully recover at least according to research. I enclose a medical history. Since then 03.2016g. your doing preventive tests and everything seemed fine. There was a period with high ASAT, ALAT anf GGT, which prescribed a Transmetil (ADEMETIONINE) 2 * 1 and had doubts about Wilson s Disease, which made studies of serum copper, Spontaneous kupriuriya for 24 hours under normal circumstances and after taking 4 tablets Kuprenil (d- penicillamine). The results were: 23/03/2016 - 1,75 mkmol / 24h 29/03/2016 after Kuprenil (d-penicillamine) - 10,8 mkmol / 24h With that they rejected the hypothesis of Wilson. Apply research from 03.2016 prescribed a Transmetil (ADEMETIONINE) 2 * 1 and Legalon (white thorn extraxt), but things did not improve after control in exploration, too MAY.2016 proved that the values again are very inflated for no apparent reason. Was again hospitalized and daily pours - Rigner Brown - Transmetil (ADEMETIONINE) ampoules - Vitamins C and B - Ursofalk (ursodeoxycholic acid) I enclose a table with a comparison of the values of the studies by 2014. And by 2016. Exploration, too hepatitis A and E are negative. In already heightened levels of liver indicators and biliurubina made a new 24-hour studies copper results are: 23/06/2016 - 2,7 mkmol / 24h 24/06/2016 after Kuprenil (d-penicillamine) -20,8 mkmol / 24h Posted a genetic study of 03/07/2016 for Wilson s disease, which wait for results. They were discharged on 01/07/2016 with suspected disease Wilson again and home treatment with Ursofalk (ursodeoxycholic acid) 3x2, Legalon (white thorn extraxt), Medrol (methylprednisolone) scheme, Transmetil (ADEMETIONINE) 2x1, Zyrtec ((Cetirizine dihydrochloride) tablets Emaneyra, Kuprenil (d-penicillamine) 2x1 Each day runs in 1 Bank 500 ml. Serum Glucose (1000 ml contains: Sodium chloride: 9.0 g, Glucose anhydrous: 50.0 g (as glucose monohydrate, 55.0 g), Sodium: 154 mmol / l, Chloride: 154 mmol / l) Results of the studies are in the attached table. The most strange is that everything was well 2 years and happened again 2 years later in the same year time (June). In these 2 years he have not had any health problems, he have eaten almost everything including mussels, sea food and etc. Nothing in his menu changed. He have been exercising also at the gym in this 2 years with medium level. Please help us find out what is going on. If something is missing or you need any extra information I will provide it. Thank you in advance.