Hello I share your concern. Since you have already taken metronidazole, so don t worry, It might be related to Viral Infection, indigestion or food allergy, in such a case metronidazole doesn t help. I would advise you to take lots of fluids like ORS lemon water and fruit juices to counter dehydration and electrolyte imbalances. In my opinion you should try to figure out any of the above mentioned triggering factor. Meanwhile continue with mebeverine hydrochloride for IBS, Have lots of fresh fruits and vegetables with dietary fiber supplement. Try to avoid fatty fried spicy and junk food and carbonated beverages. Try to allay anxiety and stress by relaxation exercises yoga and meditation. Hope you will find my answer informative and useful please feel free to ask for further clarification, I will gladly answer you. Best wishes