Thank you for this ability to chat with you. I have been taking anti-depressants for many years; in my 20 s I was diagnosed with then called manic-depressive disorder, My called bipolar 2 since I have much more depression than manic episodes. I take ativan 1 mg. 4xdaily for bad anxiety and have been taking lexapro 49 mg. daily/as 20 mg. stopped working after a short time. I have depression and anxiety and feel that the lexapro is wearing off and would like your advice as to a new SSRI you might recommend. Fora long time I took Paxil since I have panic attacks and I believe a touch of OCD...so I woulld like a drug that would address all these concerns. I will be seeing the doctor but not till the end of November. One SSRI I have not tried is Klonipin. I prefer to stay in the generiic forms for the ske of the money involved. I have taken: zoloft, celexa, prozac, paxil, and others I cannot think of right now. I need a tablet with a long shelf life to keep me feeling well. Can you suggest anything thanks in advance. AVM