Hello, Welcome to healthcare magic I understand from your query that your friend has psoriasis involving the entire body. He would need systemic / oral treatment as creams alone will not work. There are various drugs like Methotrexate, Acitretin, Cyclosporine and even phototherapy which are used to treat extensive psoriasis. These are toxic and have to be given only under the supervision of a dermatologist. These are very much available in India and we have very good treatment facilities here. You have not mentioned your place of residence. I would suggest you to consult dermatologists in good medical college attached hospitals where there are facilities to admit the patient and monitor progress. I hope this helps you. Take care.