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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Treatment For Recurring Blisters On The Roof Of Mouth

Not sure if the problems are related. I have a recurring ulcer/blister on the roof of my mouth on the border of the hard and soft palate and I have some white dots and a red line on my penis under the corona. Here s the background information; I had a sore throat immediately after unprotected oral with a stranger on a one night stand. We had sex as well, but we used a condom. 2days later I got sick and was bed ridden for 2 days, then I was completely fine. Approximately 8days after the encounter I noticed a white, hard and painless spot on the roof of my mouth on the border of the hard and soft palate. I thought nothing of it initially and it went away in a day. A week later it returned again, this time for only a night. 3 weeks it returned again for a three days and on the 4th day grew into a blister, burst and scabbed over. 3 days after it burst I got sick and developed a sore and red throat. My throat has been sore and red ever since that event and the spot seems to come an go weekly sometimes over the course of a couple of days. The one night stand occurred on the 21st of February. The blister burst on the 4th of May. I had an STD screen (serology and urine) including Herpes and HPV on the 8th of May. The results were all negative. I had another STD screen including Herpes and HPV on the 9th of June and also had a swab for viral culture of Herpes 1&2 and HPV, however the spot had been there for about 2&1/2 days and was receding, all results from all tests returned negative. However 3 days after these tests I had shooting pains in my penis and noticed four tiny white dots on the left hand side of my penis (under the corona/towards the top of the shaft, visible when I pull my foreskin back) and on the right hand side of my penis at the same sort of location I noticed a dark red line which appeared to have two tiny white dots on it. The pains lasted 2/3days. I also had an itch on the right hand side of my crotch near the base of my penis, there appeared to be redness beneath my pubic hair but I had been scratching at the itch during the day and only got a chance to actually look at night, I also suffered through maybe 5 nights of night sweats. The marks are still there, although barely visible now and with no pain. It should be noted that 14days before the penis symptoms/11days before the test, I was ill with flu like symptoms. I had another viral culture for Herpes 1&2 on the 7th of July. This time swabbed over the aforementioned areas on the penis, this to returned negative. There are more factors involved, however I m not sure how relevant they are to my diagnosis, so they might not need to be added, I understand my post is already way too long.
Mon, 12 Oct 2020
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General Surgeon 's  Response
Hello,

Recurrent blisters in mouth with genital lesion seems to be related to a sexually transmitted infection most likely. The most common cause would be Herpes simplex manifestation. A Tzanck smear of the mucosal scraping would be of much helpful for the microbiological diagnosis and cure accordingly. Many clinicians do recommend OPD based Ganciclovir or Acyclovir on clinical grounds as well.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Bhagyesh V. Patel, General Surgeon
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Suggest Treatment For Recurring Blisters On The Roof Of Mouth

Hello, Recurrent blisters in mouth with genital lesion seems to be related to a sexually transmitted infection most likely. The most common cause would be Herpes simplex manifestation. A Tzanck smear of the mucosal scraping would be of much helpful for the microbiological diagnosis and cure accordingly. Many clinicians do recommend OPD based Ganciclovir or Acyclovir on clinical grounds as well. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Bhagyesh V. Patel, General Surgeon