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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Treatment For Schizophrenia

Please let me know if there is a way to follow this up, by any medication, or any test or diet or any means. My mom has shown trends of possibility of hepatic encephalopathy, or any other brain related disease. The deep sleep kind of situation has been less frequent in the last 6-7 months. Before that, it happened 8-9 times (3-4 days deep sleep each time) in 8- 9 months (from May’10 to Jan’11) and each time serum ammonia level was found higher than normal level. She has been on diet for the last 10 months which is devoid of any animal protein, except 5-6 days where she had a piece of fish or meat. She has been taking lentils, but that too rarely. She is having medicine only for her diabetic condition and it is controlled. In the 8-9 months it has been within 80-110(fasting). She has been a psychiatric patient (schizophrenia) where the symptom has been episodic (once in 2 years or in 3 years). She talks all the time, screams at everyone, does not trust anyone and sleeps very less. She has been taking medicines for this whenever this happened earlier (her medicines include- SUNPRIZING/LITHOSUN, CHLORPROMAZINE ETC). Whenever the symptom receded, she did not take medicine anymore. And with the medicines, she recovered from the schizophrenia symptom within a month or sometimes in lesser time. The problem now is that she has started showing strong schizophrenic symptoms like earlier times; it started around 40 days back. She was taken to the psychiatrist who has been seeing for the last 15 years. I told him about her liver condition and the she has dementia. He has prescribed ‘QUTITIN 100 & LOPEZ 2’. After having Lopez 2 she was not being able to move and do her own things. I informed the doctor, he stopped LOPEZ 2. Now she is only having QUTITIN 100, for the last 2-3 days. The schizophrenic symptoms have not receded, but its bit less (it has only been 5-6 days). The concern that I have is that QUTITIN 100, in its side effect affects liver, and elevates TRANSAMINES. I’m concerned that this might again lead to the deep sleep condition. But at the same time her schizophrenic condition needs help. Please let me know if there is an alternative.
Tue, 30 Sep 2014
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Psychiatrist 's  Response
Haloperidol is a classical old drug known to be safer in patients with liver problems. Amisulpiride is one more which has very less risk of hepatic damage. Discuss with your psychiatrist about pros and cons of shifting your mother on to any of these drugs.
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Suggest Treatment For Schizophrenia

Haloperidol is a classical old drug known to be safer in patients with liver problems. Amisulpiride is one more which has very less risk of hepatic damage. Discuss with your psychiatrist about pros and cons of shifting your mother on to any of these drugs.