My friend who doesn t have the web asked me to inquire. She has chronic calluses on her hands and feet to the point sometimes she can t walk. The podiatrist has been cutting them off, causing further discomfort and damage. He has no clue what is causing them. It s only on the soles of her feet and the palms of her hands. Lotions and Vaselines are ineffective. I think it may be something lacking in her diet. Like maybe she is not producing collagen. Thank you for any help.