i had gone through your question and understand your concerns. Unless there are specific conditions or reasons why you should be taking them, betnesol is never safe to use while pregnant. It is important to understand what this medication is and why it is administered during pregnancy. First you do not mention since when your wife has BP above 140/90, as you mentioned that is 160/90. Because if your wife is detected to have BP recently after this pregnancy, that means your wife is suffering from preeclampsia. Unfortunately you did not mention whether your wife has other symptoms such as dizziness or headaches, blurred vision, swollen feet, heartburn, and protein in urine or what we call proteinuria. Because your doctor may have suspected the disease so your doctor gives betnesol injection therapy to your wife when there are chances of your wife going into a premature labor. the lungs of your unborn baby will not be developed fully until 32 to 35 weeks. betnesol injection is corticosteroids it will help to produce surfactant in your baby’s lungs, enabling them to inflate without sticking together. it has been proved to reduce the risk of intracranial hemorrhaging and other post natal threats to the pre-term babies. so if you have additional quetions or follow up questions then please do not hestitate in writing to us. i will be happy to answer your questions. i hope your wife n your baby will be healthy.