Hi & Welcome.
Incomplete data like age, gender, any associated symptoms like morning stiffness, fever, fatigue, etc.
Simvastatin is an important blood cholesterol lowering drug effectively used in the treatment of
hypercholesterolemia. Its most common side effects include myopathy (muscle pain, tenderness, or weakness),
stomach upset and liver dysfunction.
TriCor (Fenofibrate) helps reduce
cholesterol and triglycerides in the blood.
and thus used to treat
high cholesterol and high triglyceride levels. Its most common side effects include myopathy, gallstones, and stomach upset.
When taken together the risk of getting myopathy gets increased.
Based on the history given you seem to have developed myopathy involved the muscles of the hand. I would therefore advise you to stop taking these medications after consulting your doctor and an alternative effective but safer medication like bile acid binding resin (
Cholestyramine) to be taken to lower the cholesterol and triglycerides.
Alternatively your doctor might consider the use of Fluvastatin extended release, every-other-day dosing of
Atorvastatin or rosuvastatin, and twice weekly Rosuvastatin. These statins have a lower potential to cause myopathy.
Besides these, you also need to be properly evaluated to rule out the possibility of
rheumatoid arthritis by relevant lab tests such as CBC, ESR, Rh factor, Anti nuclear antibodies, Anti CCP, etc.
Hope the advice given above would be useful.