Hello. I am a female, 57 years old. For the past few weeks, I have been experiencing an intermittent, severe rash with itching. The symptoms last for 10-15 minutes, during which I cannot stop scratching. The rash displays rather large welts, similar to hives. The location is varied. Sometimes on my thigh, sometimes on my chest, or my arm - wherever. I have never experienced anything like this before, although in the past I have had hives from extreme nervous situations. I have severe OA and Depression, long standing. I take Furosemide (for many years), Effexor (7 months), Colace, Naprosyn prn, Vitamin B12 weekly. Please advise if you think this is something I need to worry about. It is most bothersome.