I am a 48 year old female, 350 pounds, given 2 doses of diflucan for a yeast infection over 2 weeks ago. I have horrible soreness, itching, burning, redness, swelling, of my vagina and going back towards my anus. The skin feels dry, and literally rolls up when you touch it. The diflucan helped for a few days, but then all of the above mentioned came back twice as bad.