Over the past 2 weeks I have had what appears to be an allergic reaction to something . It starts on my face, becoming red and swollen - like a bad sunburn, then progresses to my arms, torso and lower legs. We are currently thinking it might have to do with my new/used car and possibly new clothing. It seems to be systemic as opposed to a contact dermatitis because it spreads and does not seem to be confined to an area touching something. It has occurred 4 x in the past 2 weeks. Each time I was in or had just left my car. 2x I was wearing a new shirt (different shirts) that had not yet been washed. Each time I took benadryl, 1x I took a shower and one time I applied cool compress. It does not seem need to be washed off.