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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Treatment For Thrombocytopenia Purpura And Hepatitis C

Years ago I had Hep. a or b, not sure anymore,however, I was recently diagnosed with Ideopathic thrombocytopenia purpura and now have just been diagnosed with hep. C my platelets are very low. am taking N-Plate. Is there any cure or hope for me??? Marge and thank you for answering my question.
Fri, 22 Jul 2016
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Ayurveda Specialist 's  Response
Dear
Thanks for raising your concern and I would like to answer your query in three aspects:

1. Since you were earlier diagnosed with Hep. A/B and now with C and since all three are ateiological cause for Chronic Hepatitis thus check for the same with:
. Liver function tests (serum bilirubin,SGOT & SGPT,Prothrombin time,alkaline phosphatase,serum proteins)

. Serological diagnosis:
HbeAg and positive HBV DNA (in hep. B)
Anti-HAV of IgM class in hep. A
Anti-HCV & HCV RNA in hep. C infection

2. As you are now diagnosed with Hep. C infection which accounts for more than 90% of post transfusion hepatitis, as such there is no active or passive protection and development of vaccine is in progress and also the prognosis is moderate (not good, not bad) so one can manage the disease by
. Low fat,high carbohydrate diet, plenty of fluids,avoid close physical contact, alcohol, sharing combs/razor.
. Regular surveillance on clinical parameters as well as liver function tests.
. Reassurance as recovery is the rule in majority.

3. ITP (Idiopathic Thrombocytopenic Purpura) usually occur in women between 20-40 years of age and there is gradually developing petechiae-purpura over skin, bleeding from gums,menorrhagia,epistaxis or hematuria, so best management required is:
. Watch for signs of internal hemorrhage
. Check stool for occult blood
. Check regularly with Bleeding time (BT) and platelet count (PC)
. Avoid pain killer (except paracetamol),use soft tooth brush and electric razor

. Platelet or fresh blood transfusion is ideal and/or splenectomy with pneumococcal, H. influenzae and meningococcal vaccination

PS. 1 unit of platelet transfusion raise the count by 10000/mm cube.
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Suggest Treatment For Thrombocytopenia Purpura And Hepatitis C

Dear Thanks for raising your concern and I would like to answer your query in three aspects: 1. Since you were earlier diagnosed with Hep. A/B and now with C and since all three are ateiological cause for Chronic Hepatitis thus check for the same with: . Liver function tests (serum bilirubin,SGOT & SGPT,Prothrombin time,alkaline phosphatase,serum proteins) . Serological diagnosis: HbeAg and positive HBV DNA (in hep. B) Anti-HAV of IgM class in hep. A Anti-HCV & HCV RNA in hep. C infection 2. As you are now diagnosed with Hep. C infection which accounts for more than 90% of post transfusion hepatitis, as such there is no active or passive protection and development of vaccine is in progress and also the prognosis is moderate (not good, not bad) so one can manage the disease by . Low fat,high carbohydrate diet, plenty of fluids,avoid close physical contact, alcohol, sharing combs/razor. . Regular surveillance on clinical parameters as well as liver function tests. . Reassurance as recovery is the rule in majority. 3. ITP (Idiopathic Thrombocytopenic Purpura) usually occur in women between 20-40 years of age and there is gradually developing petechiae-purpura over skin, bleeding from gums,menorrhagia,epistaxis or hematuria, so best management required is: . Watch for signs of internal hemorrhage . Check stool for occult blood . Check regularly with Bleeding time (BT) and platelet count (PC) . Avoid pain killer (except paracetamol),use soft tooth brush and electric razor . Platelet or fresh blood transfusion is ideal and/or splenectomy with pneumococcal, H. influenzae and meningococcal vaccination PS. 1 unit of platelet transfusion raise the count by 10000/mm cube.