Hi Dear !! Thanks for your query to HCM . Read and reviewed your query and health concerns. My opinion- IN the given situation, You seems to be having-Diabetic Nephropathy with mild CKD(Chronic kidney Disease). Confusion lately observed is due to uncontrolled diabetes,as the brain CT is normal. Do s Suggested- You need to concentrate on correction of diet / exercises/ and low protein,low salt diet with medicines under care of Diabetologist and Nephrologist, who wold treat it according to the investigation and clinical assessment. Old TB revival need to be observed being diabetic.TB revival could be ruled out in view of confusion before planning any further care in your case. IGRA blood test-for ruling out-active TB infection needs to be repeated to rule out activated TB lung infection. Other causes need to be ruled out after proper check up physically and after investigation from Physician/ Diabetologist and Nephrologist- if need be. Rule out other causes,before concluding treatment on above lines. This briefing reply is on facts submitted, which need to be verified from your attending doctors, with whom you can check before starting further changes in the treatment of your dad. Hope this would help you to plan further of this complex illness of yours. If need be, update any health issue 24 x 7 by a direct question to ME, at following HCM link-http://doctor.healthcaremagic.com/Funnel?page=askDoctorDirectly&docId=70229 Dear, if satisfied,Don t forget to close this query with YOUR pleasing feedback comments to rate this reply and service, to boost the morale of incoming Emergency patients like YOU, at HCM services. If you want to update more details and ask more update queries , You are most Welcome herewith !! Good Day!! Wishing Good Healthy Life in time to come!! Dr.Savaskar M.N. Senior Surgical Specialist M.S.Genl-CVTS