Hi There - my mother is currently taking various medication for urinary tract infection, blood pressure, osteoporosis, depression, and in 2014 she had a mastectomy and she also takes medication for that (she will take this for the next 5 years) I have just spent the last week with her and she cannot sleep, she seems to be in pain with her urinary tract infection, and she is extremely down. She has said that she has never felt so bad since she started taking all of the medication she is currently on. She is 79 years old and I am worried that this mixture of medication is not agreeing with her.