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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Ways To Manage Amitriptyline Withdrawal Symptoms

Trying to get off the drug perphenazine/amitriptyline 2-10. Have been taking the drug over 30 years. Regular dose was one a day, have cut down to 2 a week. Not feeling well. Stomach nervousness and a lot of irregular heart beats, maybe pvcs. Is this normal?
Thu, 9 Mar 2017
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Ayurveda Specialist,  's  Response
hi There

upset stomach and palpitations are withdrawal symptoms of Amitriptyline and this is normal. You have dropped Amitriptyline to very low dose that is why you are facing all these symptoms.

Amitriptyline should not be abruptly or rapidly discontinued due to the potential of severe withdrawal symptoms. It is recommended to do a slow taper to minimize symptoms. So should start taking on alternative days for 15 days then after two days for next 15 days. Increase no of days after 15 days . It will decrease the withdrawal symptoms.
You can add a supportive treatment with Omega3 capsule and Tart cherry .

Good Luck
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Suggest Ways To Manage Amitriptyline Withdrawal Symptoms

hi There upset stomach and palpitations are withdrawal symptoms of Amitriptyline and this is normal. You have dropped Amitriptyline to very low dose that is why you are facing all these symptoms. Amitriptyline should not be abruptly or rapidly discontinued due to the potential of severe withdrawal symptoms. It is recommended to do a slow taper to minimize symptoms. So should start taking on alternative days for 15 days then after two days for next 15 days. Increase no of days after 15 days . It will decrease the withdrawal symptoms. You can add a supportive treatment with Omega3 capsule and Tart cherry . Good Luck