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TB Meningitis. Treated With Rifampicin, Pyriniazinamide And Isonazid. Problem Of Diplopia. Advice Complete Cure Of Problems?
My wife Ayrin Sultana (23 years old) was suffering from TB meningitis, admitted to Yamaguchi University hospital Japan on July05, 2013. Now doctors are sure about her TB infection but not type of TB pathogens. However last 3 weeks she is under treatment of TB meningitis with Rifampicin, ethambutol, pyriniazinamide and isoniazid. After 7-8 days, Doctors omitted ethambutol while my wife could not see clearly (everything was dark), now bit improved. She has another problem of diplopia. Her left eye pupil is not moving completely to the left corner. Doctors tried to find out optic nerve dysfunction by MRI scanning but could not detect. However, please let me know about your assumption regarding the complete cure of eye problem after meningitis treatment.
Sat, 17 Aug 2013
Hello,
Thanks for the query to H.C.M. FORUM.
As your wife is taking rifampicin, isoniazide & pyrazinamide from last three weeks.
The side effects of isonizide besides are peripheral neuritis, OPTIC NEURITIS & VISUAL DISTURBANCES .
However it is very difficult to say what is the reason of diplopia ( double vision).
In my opinion your wife is very sensitive to ISONIZIDE salt and this may have damage ( mild & partial , transient ).
In my opinion consult your treating doctors and discuss about the side effects of isonizide and reassess the line of treatment .
Consult an ophthalmologist and get his opinion.
Hope I have answered your question.
If further nay question I will reply.
Good luck for your wife.
Dr. HET
Thanks for the query to H.C.M. FORUM.
As your wife is taking rifampicin, isoniazide & pyrazinamide from last three weeks.
The side effects of isonizide besides are peripheral neuritis, OPTIC NEURITIS & VISUAL DISTURBANCES .
However it is very difficult to say what is the reason of diplopia ( double vision).
In my opinion your wife is very sensitive to ISONIZIDE salt and this may have damage ( mild & partial , transient ).
In my opinion consult your treating doctors and discuss about the side effects of isonizide and reassess the line of treatment .
Consult an ophthalmologist and get his opinion.
Hope I have answered your question.
If further nay question I will reply.
Good luck for your wife.
Dr. HET
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