Hi, I understand your concern and congratulate you that you are so vigilant in choosing your drugs. Oral contraceptive pills are an excellent method of preventing pregnancy but all of them do have a few disadvantages. They all tend to increase the risk of blood clots but this happens more in elderly women, usually those that are debilitated or suffering from liver, heart or diseases of blood vessels. Drosperinone has been found to have a slightly higher risk of clotting than the other pills. Also, most of the newer pills do not cause hair growth but drosperinone itself decreases hair growth in women that have a high level of male sex hormones causing hair growth. If you do not have any such issue then any of both the drugs is a good choice. Regarding weight gain, this is unpredictable and depends upon ones own personal body composition and behavior as well as lifestyle factors like a sedentary lifestyle. If you feel concerned go ahead and use lo ovral. I hope I was able to help you. Have a nice day and thanks for using HCM!