Sudden onset of thigh pain that did not respond to vicadin or lyrica, heat or cold treatment. It is a burning pain that disrupts sleep. Several days later a rash on the lower calf developed. According to a doc, this did not look like an allergic reaction to medication. Person lives in Texas. ? a reaction to an insect bite yet according to him no bite seen. He also ate raw octopus and other fish at an asian restaurant a day earlier. This has been going on for almost two weeks, Any ideas?