Hello Good Evening, You said that you frequently miss the periods, then why you should not go to detect the reasons behind it, this can be due to any other medical reason like PCOS (Polycystic ovary syndrome). PCOS produces symptoms in approximately 5% to 10% of women of reproductive age (12–45 years old). It is thought to be one of the leading causes of female sub-fertility and the most frequent endocrine problem in women of reproductive age. The principal features are anovulation, resulting in irregular menstruation, amenorrhea, ovulation-related infertility, and polycystic ovaries; excessive amounts or effects of androgenic (masculinizing) hormones, resulting in acne and hirsutism; and insulin resistance, often associated with obesity, Type 2 diabetes, and high cholesterol levels. The symptoms and severity of the syndrome vary greatly among affected women. Urine pregnancy test depends on beta HCG hormone levels, not on persons, so it is senseless to say that it is not working for me . This is not the problem of the test kit, something can be missing in you i.e. ovulation. So go for a USG to diagnose a PCOS f/b go to gynecologist for proper examinations and investigations to detect the cause of your sub-fertility. Regards, Dr. Naresh Jain.