Hello Mrs ramyanalluri, You have mentioned two different aspects leading to
infertility.
PCOS is a condition where there is problem with ovulation that is egg release due to
hormonal imbalance. There are methods to correct that problem helping the egg release. You also can help yourselves by regular excercise and maintaining a healthy weight and diet. Another aspect is
mycobacterium tuberculosis in the womb. This has to be diagnosed either by a method called TB-PCR (RNA or DNA, DNA being more specific for
active tuberculosis) or by histopathology. It is more specific to have histopathological diagnosis. You need to be treated with antitubercular medication for that. But if there is extensive involvement of womb with tuberculosis, chances of conception are poor. Extensive involvement may lead to abnormality in your periods as well. Regarding natural killer cells- where are they found? in the blood or in the womb? If it is in the womb- not to worry as they are required for proper
implantation of
pregnancy. They are a type of cells which are part of our immune system. If there is tuberculosis in the tubes, chances of spontaneous conception are poor, where you might need assisted methods for conception.
If both these issues are resolved you can hope for a conception.
Dr Radhika kandula
MBBS,DNB(OBG)FNB(Reproductive medicine)