I resonate with this question (and answer) in that I also have no functioning spleen and Type 2 diabetes. Below, Dr. Am.,/.put says, Hba1c results are usually accurate, but not having spleen would affect the result slightly and readings might be a bit on higher side than usual. In other words ... without a spleen the Hba1c results are inaccurate and read high ... therefore one can infer that a reading of 6, for example, means that the patient is functionally at a level of 5.9 or lower? Is that the case? I m looking for clarification. It seems (to phrase this casually) that having a functioning spleen would be a useful item to have, but especially so with diabetes. Although that makes sense on a pedestrian level, can someone explain exactly what the spleen does that helps the Hba1c count stay low?