Hi, Thank you for posting your query. I have noted the details of your mother. It is unfortunate that she suffered a major stroke at a relatively young age. The cause of stroke is related to heart disease. The PT/INR is maintained by using adequate dose of warfarin or acitrom tablets. If the dose is less, the blood becomes thick, leading to ischemic stroke (lack of blood flow to the brain). The likely outcome and improvement depends on the exact location and size of stroke. So, if you can send the MRI or CT scan of brain report, it would be helpful in predicting the chances of recovery. In the meanwhile, the supportive treatment, physiotherapy, etc should be continued. I hope my answer helps. Please get back if you have any follow up queries or if you require any additional information. Wishing you good health, Dr Sudhir Kumar MD (Internal Medicine), DM (Neurology) Senior Consultant Neurologist Apollo Hospitals, Hyderabad, India Click on this link to ask me a DIRECT QUERY: http://bit.ly/Dr-Sudhir-kumar My BLOG: http://bestneurodoctor.blogspot.in