I have no idea if there is actually a doctor on the other end of this email but, what the heck....I am a 39 year old male, 175 lbs, and on 200mg of Buproprion per day. I have never used recreational drugs in my life. I am considering eating some marijuana cookies with my boyfriend (yes, I'm gay). I have been researching the possible side effects of mixing marijuana with buproprion (wellbutrin) and there are so many conflicting statements. One says that mixing the two would cause a severe psychotic episode and then other places have people posting experiences that say they have never had a single side effect from mixing the two. Is this truly just an individual situation and everyone will react differently? There's everything from....my high was the same, to it was the worst thing I've every experienced. Would eating the marijuana in cookies have a different result? What are the risks of mixing marijuana (eating) and wellbutrin/buproprion?