Crestor (rosuvastain) is a statin. Statins are associated with muscle symptoms, neuropathy and sometimes new onset diabetes mellitus. Nevertheless, the recent opinion is that the benefits still outweigh the risk. Statins are considered most effective in decreasing lipid levels. You can continue statins by discussing about the above risks with your prescriber. Also you can go for other drugs like ezetamibe that does not have such side effects. But the effectiveness is also less. And yes physical exercise and other lifestyle modifications will also help. You have the option of giving a trial of lifestyle modifications. But if you were my patient I would have advised lifestyle modifications with low dose medications for optimal control. I hope the above information helps you. Thanks for writing into healthcaremagic. Have a wonderful day.