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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Are The Side Effects Of NIDDM Medicine?

I am a 56 year old male, obese 275 lbs 6 2 , pack a day smoker, with sleep apnea, not adherent to CPAP, Ihave NIDDM and take metformin and glipizide with a controlled HgbA1C of about 6.4 yet I have numbness of my right foot with occasional seering pain traveling down the lateral aspect of my right leg, and darkening, as if dirty, of dorsal feet with clear creases within. .Is this all consistent with NIDDM or more.
Tue, 11 Oct 2016
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General & Family Physician,  's  Response
Dear Sir, Hi & Welcome to HCM.
I can understand your concern.

Based on the history given in your query;

1. Your blood glucose seems to be well controlled with the prescribed medications Metformin & Glipizide. They are generally safe and well tolerated, however they can cause the following side effects:

Metformin can cause stomach upset, cramps, diarrhea, lactic acidosis (which is rare).
Glipizide can cause hypoglycemia (low blood glucose), increased appetite, weight gain or allergic reactions.

2. You seem to be suffering from a condition called Thromboangiitis obliterans (TAO) which commonly occurs in chronic smokers with heavy tobacco use.

At the outset, you must stop smoking completely. As absolute discontinuance of tobacco use can prevent the progression of TAO.

Besides, you can take certain multivitamins containing Methylcobalmin & Alfa lipoic acid to get relief from the painful nerves.

Hope this will help.
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What Are The Side Effects Of NIDDM Medicine?

Dear Sir, Hi & Welcome to HCM. I can understand your concern. Based on the history given in your query; 1. Your blood glucose seems to be well controlled with the prescribed medications Metformin & Glipizide. They are generally safe and well tolerated, however they can cause the following side effects: Metformin can cause stomach upset, cramps, diarrhea, lactic acidosis (which is rare). Glipizide can cause hypoglycemia (low blood glucose), increased appetite, weight gain or allergic reactions. 2. You seem to be suffering from a condition called Thromboangiitis obliterans (TAO) which commonly occurs in chronic smokers with heavy tobacco use. At the outset, you must stop smoking completely. As absolute discontinuance of tobacco use can prevent the progression of TAO. Besides, you can take certain multivitamins containing Methylcobalmin & Alfa lipoic acid to get relief from the painful nerves. Hope this will help.