I am taking paxidep cr 25 for the last 6 months - daily 1 tablet. I am also on migraine medication (naxdom 500) on sos basis. After taking paxidep cr 25, my migraine headaches have increased substantially. Also, frequency and intensity of headaches have increased. My intake of naxdom 500 is around 10-15 tablets/ week. Also, I am experiencing severe uneasiness in case of slight change in tempreature, sweating (here it s winters now). 1) If there is any reaction of paxidep cr 25 with naxdom 500. 2) I am worried, if there are any serious side effects of paxidep. 3) should i leave this medicine and if yes, then how? is there any way of withdrawing paxidep ( my doctor had prescribed paxidep for 2-2.5 years)