It s not clear what causes Hodgkin s lymphoma. Doctors know that most Hodgkin s lymphoma occurs when an infection-fighting cell called a B cell develops a mutation in its DNA. The mutation tells the cells to divide rapidly and to continue living when a healthy cell would die. The mutation causes a large number of oversized, abnormal B cells to accumulate in the lymphatic system, where they crowd out healthy cells and cause the signs and symptoms of Hodgkin s lymphoma. Various types of Hodgkin s lymphoma exist. The type is based on the types of cells involved in your disease and their behavior. Your type determines your treatment options. Symptoms: Swollen lymph nodes Swollen lymph nodes Hodgkin s lymphoma signs and symptoms may include: Painless swelling of lymph nodes in your neck, armpits or groin Persistent fatigue Fever and chills Night sweats Unexplained, rapid weight loss Itching Increased sensitivity to the effects of alcohol or pain in your lymph nodes after drinking alcohol I hope you happy with information kindly rate it. thank you.