What are the symptoms of an elevated ammonia level? My 30yr old son takes Depakote for a seizure disorder and bi-polar he also has autism, so I can t ask him about how he feels. For the past few weeks he has been very tired, clumsy, his eyes are beginning to take on a yellow hue though no one seems to notice this but me, and he has black circles under his eyes. All the usual suspects have been ruled out, infection, anemia etc. I was just sitting here at dinner watching fall asleep at the table and the thought popped into my head perhaps his ammonia level is elevated. I can t find much info on what the symptoms, so any information would be much appreciated before I drag him through another blood test. Thank you for your time