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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Are The Symptoms Of Elevated Ammonia Level?

What are the symptoms of an elevated ammonia level? My 30yr old son takes Depakote for a seizure disorder and bi-polar he also has autism, so I can t ask him about how he feels. For the past few weeks he has been very tired, clumsy, his eyes are beginning to take on a yellow hue though no one seems to notice this but me, and he has black circles under his eyes. All the usual suspects have been ruled out, infection, anemia etc. I was just sitting here at dinner watching fall asleep at the table and the thought popped into my head perhaps his ammonia level is elevated. I can t find much info on what the symptoms, so any information would be much appreciated before I drag him through another blood test. Thank you for your time
posted on Mon, 28 Apr 2014
Twitter Mon, 8 Sep 2014 Answered on
Twitter Mon, 8 Sep 2014 Last reviewed on
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General & Family Physician,  's  Response
Hi and thank you so much for this query.

I am so sorry to hear about these symptoms that your son has been experiencing. Unless the liver is not functioning normally, there would be no increased ammonia levels. With you reporting a yellowish discoloration of his eyes, it could be possible that he has an ongoing liver disease. Ammonia in excess levels would induce sleepiness, obnibulation and eventually coma. This would be unlikely without a severe liver disease. Get hi to the doctors should you be concerned but ammonia per se without a suggestive history would be unlikely.

I hope this helps. I wish you well. Thank you so much for using our services and do feel free to ask for more information and clarifications if need be.
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What Are The Symptoms Of Elevated Ammonia Level?

Hi and thank you so much for this query. I am so sorry to hear about these symptoms that your son has been experiencing. Unless the liver is not functioning normally, there would be no increased ammonia levels. With you reporting a yellowish discoloration of his eyes, it could be possible that he has an ongoing liver disease. Ammonia in excess levels would induce sleepiness, obnibulation and eventually coma. This would be unlikely without a severe liver disease. Get hi to the doctors should you be concerned but ammonia per se without a suggestive history would be unlikely. I hope this helps. I wish you well. Thank you so much for using our services and do feel free to ask for more information and clarifications if need be.