Hello, Gerd can cause all these symptoms but to worry is that it s not responding to esomeprazole so I feel it s time you need to see a gastroenterologist who would take a more detail history and investigation if needed. I suggest such patient check his breath test for h pylori and eradication if positive. The rule of lifestyle modification in Gerd still stands high example avoid small meals at a time, avoid spicy food, avoid smoking, alcohol, elevating the head end of the bed in the night, use of antacids. You may well need an endoscopy if things don t help a lot. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Mahboob Ur Rahman