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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Abdominal Distention After Taking Jakafi?

Yes, I m so upset. I started Jakafi for mylofibrosis on Monday of last week and I look pregnant and I m up already by 5 lbs. maybe in the scream of things this means nothing but to me it s more then I can handle. How much more of me can this PV and now mylofibrosis take of me. It took away my bone pain and my spleen issue but I m left with a big belly. I take pride in how I look and no one knowing I m so sick. I like looking good. I hate this illness. I m so sad and depleted.
Thu, 7 Nov 2019
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General Surgeon,  's  Response
Hello,

* It is the gastric upset with the consumption of Jakafi used for myelofibrosis, responsible for abdomen distension.

* I quote here following guidelines for your best recovery

- Take an antacid or proton pump inhibitor as omeprazole with sips of water on an empty stomach.
- Consume Jakafi after meals with milk.
- Manage to have soft, regular bowel evacuations with high fiber diet and bulk-forming laxative as per the need.
- Remain ambulatory and have exercises of allowable range as per the allowance via myelofibrosis issue.
- Steroid medications if along with the same, must be discussed with the treating physician to discontinue or adjust the dosage.
- Control body weight, blood sugar and cholesterol levels.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr Bhagyesh V. Patel, General Surgeon
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What Causes Abdominal Distention After Taking Jakafi?

Hello, * It is the gastric upset with the consumption of Jakafi used for myelofibrosis, responsible for abdomen distension. * I quote here following guidelines for your best recovery - Take an antacid or proton pump inhibitor as omeprazole with sips of water on an empty stomach. - Consume Jakafi after meals with milk. - Manage to have soft, regular bowel evacuations with high fiber diet and bulk-forming laxative as per the need. - Remain ambulatory and have exercises of allowable range as per the allowance via myelofibrosis issue. - Steroid medications if along with the same, must be discussed with the treating physician to discontinue or adjust the dosage. - Control body weight, blood sugar and cholesterol levels. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr Bhagyesh V. Patel, General Surgeon