Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties
159 Doctors Online

By proceeding, I accept the Terms and Conditions

Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

HCM Blog Instant Access to Doctors
HCM BlogQuestions Answered
HCM Blog Satisfaction

What Causes Aggressive Behavior With Drop In Sugar Levels On Taking ATK4?

My dad aged 68 years and diabetic is diagonised with TB recently through CT scan. He has been prescribed to use ATK4 medicines which he took along with regular medicines including Glypride for sugar. He started the ATK4 medince last Tuesday (15th Nov). After couple of days, he sudenly started behaving aggressively with sugar level dropping to 39 mg/dl. He got admitted immedialy. Also his sodium level has dropped considerably. A doctor then visited told him ATK4 is a bit stronger for his age and asked us to stop this immediately and to switch over to Tab Glevo 500 mg, Benadon and combinex. He also told us liver got damaged because of ATK4. Not his sugar as well as sodium is restored to somewhat normal level for now. He got discharged from hosptial yesterday with advise that his food intake should be good going forward Can you suggest stopping ATK4 is right? Do we need to restart it or TB can be cured with Tab Glevo 500 mg, Benadon and combinex? Also we were asked to stop Glypride for few more days, when do we restart it?
Tue, 24 Nov 2020
Report Abuse
Internal Medicine Specialist 's  Response
Hi,

Combunex is combination of Ethambutol/isoniazid, thus avoiding Rifampicin in AKT4 which is hepatotoxic in few people. Adding Glevo (levofloxacin) is correct apart from it. If you developed liver toxic symptoms again, you need to stop Isoniazide. Trial and error, Ethambutol is least liver toxic, you can continue stoping glyburide and waiting for some time reasonable

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Suneel V. Babu, Internal Medicine Specialist
I find this answer helpful

Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..
Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer. For a more detailed, immediate answer, try our premium service [Sample answer]
Share on
 

Related questions you may be interested in


Recent questions on Tuberculosis


Loading Online Doctors....
What Causes Aggressive Behavior With Drop In Sugar Levels On Taking ATK4?

Hi, Combunex is combination of Ethambutol/isoniazid, thus avoiding Rifampicin in AKT4 which is hepatotoxic in few people. Adding Glevo (levofloxacin) is correct apart from it. If you developed liver toxic symptoms again, you need to stop Isoniazide. Trial and error, Ethambutol is least liver toxic, you can continue stoping glyburide and waiting for some time reasonable Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Suneel V. Babu, Internal Medicine Specialist