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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Anger And Muscle Weakness While On Bupropion And Propranolol?

I am a mental health therapist with an APN writing prescriptions for patients. A patient taking bupropion hcl oral and propranolol oral - is complaining about anger, hands and feet feel funny and he said I don t know I just feel retarded right now. He has been taking this combination of drugs for awhile. Thoughts?
Fri, 2 Dec 2016
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General & Family Physician 's  Response
Hello,
Since you are a doc I'm just giving you a short explanation. Bupropion's side effect by itself is agitation and anger. If the patient has been given this for smoking cessation then the effect of withdrawal can add up the effect.
I believe he is on the "honeymoon" period of bupropion. Please you will find more when you search for the honeymoon effect of bupropion.
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What Causes Anger And Muscle Weakness While On Bupropion And Propranolol?

Hello, Since you are a doc I m just giving you a short explanation. Bupropion s side effect by itself is agitation and anger. If the patient has been given this for smoking cessation then the effect of withdrawal can add up the effect. I believe he is on the honeymoon period of bupropion. Please you will find more when you search for the honeymoon effect of bupropion.