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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Black Mole Like Spots On The Scrotum And Testicles?

Hi I have just noticed there are around 10-12 black mole like spots on my scrotum and testicles... As far as I remember I did not had them before. I am in a relationship in last four months and my girl friend told me recently that she had been treated for cervical cancer due to HPV. I am extremely scared that these spots may be due to HPV. They don t hurt or itch. Please help
Tue, 11 Sep 2018
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General & Family Physician 's  Response
Hi,

Black spots on your scrotum are usually caused by a condition called angiokeratoma of Fordyce. These spots are made up of blood vessels that have expanded, or dilated, and become visible on the surface of your skin. They may feel bumpy and rough to the touch, and they’re normally dark purple or red rather than deep black.

Angiokeratoma of Fordyce can also appear on the shaft of your penis and around your inner thighs. These spots usually aren’t cause for concern, especially if you don’t have any other symptoms. Keep reading to learn why these spots appear, other symptoms you should watch out for, and what to expect from treatment.

Cause: In many cases, the exact cause of angiokeratoma of Fordyce is unknown. Some research suggests that high blood pressure (hypertension) in the veins of your scrotum may play a role in their appearance. They may also be more likely to appear if you’ve ever experienced:

1. Hemorrhoids
2. Irritable bowel syndrome
3. Chronic constipation
4. Fabry disease (FD) is one of the only known causes of angiokeratoma of Fordyce. This condition is extremely rare, happening in only about 1 out of every 40,000 to 60,000 men.

FD results from a mutation in your GLA gene. This gene is responsible for producing an enzyme that helps cells break down fat. With FD, your cells can’t break down a certain type of fat that then accumulates throughout your body. Having too much of this fat in your body can hurt the cells in your heart, kidneys, and nervous system.

You should see your doctor as soon as you can if you notice black spots on your scrotum. They’re usually harmless, but your doctor will help diagnose or rule out any conditions like FD. Your doctor will perform a physical examination and ask you about your medical history.

Because FD is passed down genetically, you may also be asked about your family’s medical history. Other tests your doctor may perform include the following:
1. Imaging tests, such as CT scans or X-rays, are used to look at parts of your body that might be affected by an underlying condition. This includes your heart or kidneys.
2. Lab tests are used to check for the mutation that causes FD. Your doctor may do this with a blood, urine, or skin tissue sample.
3. Tissue samples (biopsies) are used to test for the enzyme that breaks down fat in cells. A biopsy can also test the spots for cancerous cells to determine if they’re melanomas, which result from a rare form of skin cancer.
Treatment: On their own, angiokeratoma of Fordyce don’t need treatment. But if the spots are causing irritation or otherwise bothering you, talk to your doctor about removal. They may recommend one of the following removal techniques:

1. Electrodesiccation and curettage (ED&C). Your doctor uses a local anesthetic to numb the area around the spots. Once the area is numb, they use tools to scrape the spots off and remove the tissue.
2. Laser removal. Your doctor uses laser techniques, such as a pulsed dye laser, to remove the expanded blood vessels that are causing the black spots.
3. Cryotherapy. Your doctor freezes the tissue around the black spots and remove them. FD can be treated with a medication called agalsidase beta (Fabrazyme).

This medication needs to be injected regularly to help your body break down the extra fat that has built up in your cells. The GLA gene mutation prevents your body from creating enough of a certain enzyme to break the fat down naturally. Your doctor may also prescribe medication to treat pain in your hands and feet. This includes Gabapentin (Neurontin) or Carbamazepine (Tegretol).

Hope I have answered your query. Let me know if I can assist you further.
Regards,
Dr. Sanjay Kini, General & Family Physician
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What Causes Black Mole Like Spots On The Scrotum And Testicles?

Hi, Black spots on your scrotum are usually caused by a condition called angiokeratoma of Fordyce. These spots are made up of blood vessels that have expanded, or dilated, and become visible on the surface of your skin. They may feel bumpy and rough to the touch, and they’re normally dark purple or red rather than deep black. Angiokeratoma of Fordyce can also appear on the shaft of your penis and around your inner thighs. These spots usually aren’t cause for concern, especially if you don’t have any other symptoms. Keep reading to learn why these spots appear, other symptoms you should watch out for, and what to expect from treatment. Cause: In many cases, the exact cause of angiokeratoma of Fordyce is unknown. Some research suggests that high blood pressure (hypertension) in the veins of your scrotum may play a role in their appearance. They may also be more likely to appear if you’ve ever experienced: 1. Hemorrhoids 2. Irritable bowel syndrome 3. Chronic constipation 4. Fabry disease (FD) is one of the only known causes of angiokeratoma of Fordyce. This condition is extremely rare, happening in only about 1 out of every 40,000 to 60,000 men. FD results from a mutation in your GLA gene. This gene is responsible for producing an enzyme that helps cells break down fat. With FD, your cells can’t break down a certain type of fat that then accumulates throughout your body. Having too much of this fat in your body can hurt the cells in your heart, kidneys, and nervous system. You should see your doctor as soon as you can if you notice black spots on your scrotum. They’re usually harmless, but your doctor will help diagnose or rule out any conditions like FD. Your doctor will perform a physical examination and ask you about your medical history. Because FD is passed down genetically, you may also be asked about your family’s medical history. Other tests your doctor may perform include the following: 1. Imaging tests, such as CT scans or X-rays, are used to look at parts of your body that might be affected by an underlying condition. This includes your heart or kidneys. 2. Lab tests are used to check for the mutation that causes FD. Your doctor may do this with a blood, urine, or skin tissue sample. 3. Tissue samples (biopsies) are used to test for the enzyme that breaks down fat in cells. A biopsy can also test the spots for cancerous cells to determine if they’re melanomas, which result from a rare form of skin cancer. Treatment: On their own, angiokeratoma of Fordyce don’t need treatment. But if the spots are causing irritation or otherwise bothering you, talk to your doctor about removal. They may recommend one of the following removal techniques: 1. Electrodesiccation and curettage (ED&C). Your doctor uses a local anesthetic to numb the area around the spots. Once the area is numb, they use tools to scrape the spots off and remove the tissue. 2. Laser removal. Your doctor uses laser techniques, such as a pulsed dye laser, to remove the expanded blood vessels that are causing the black spots. 3. Cryotherapy. Your doctor freezes the tissue around the black spots and remove them. FD can be treated with a medication called agalsidase beta (Fabrazyme). This medication needs to be injected regularly to help your body break down the extra fat that has built up in your cells. The GLA gene mutation prevents your body from creating enough of a certain enzyme to break the fat down naturally. Your doctor may also prescribe medication to treat pain in your hands and feet. This includes Gabapentin (Neurontin) or Carbamazepine (Tegretol). Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Sanjay Kini, General & Family Physician