Hello, If scans are done and lung clots are ruled out at the cause of the chest pain and shortness of breath, very likely her symptoms are due to anxiety. This is likely the case as her symptoms happen at night when she laying down and not exercising. She will need to take pain killers before bed and also try to avoid coffee, alcohol, smoking and energy drinks. Some psychotherapy may be helpful as well. In some cases, if symptoms are bothersome and last more than two weeks, treatment for anxiety is indicated (SSRI drugs). I hope this answers your query. I remain at your disposal in case further medical assistance is needed. Regards, Dr. Antoneta Zotaj General and Family Physician