Hi,I have had problem with being REALLY cold, feet, butox, breast tissue ,etc. This has been going on for about two years. I tried to relieve my symptoms with vasopressin, it seemed to work for awhile but quit.The only way I can get relief is either direct heat on the areas or lortab. I now am anemic not due to low iron. I also have widespread bone pain. Back \, hips sternum, feet, fingers are horrible. Had to have surgery to releases The first to fingers on my right hand. Theese are just a few symptoms off the top. Thank you Linda