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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Elevated ALT Level?

last week my alt was219 and my ast was 99. this week the alt is 261 and my ast is 99. I have not ha any alcohol in nerly 6 weeks. Last Sept my alt was 64 and my a st was normal at 35. I am wondering what could cause such a drastic change in 1 week. My us was normal & hepatits panel was negative.
Mon, 27 Feb 2017
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General & Family Physician,  's  Response
Hi and welcome to Healthcaremagic. I understand your concerns.
If viral hepatitis and alcoholic hepatitis are ruled out then there are several other conditions which could lead to ALT elevation. It includes autoimmine hepatitis and gilberts diseases and you need extended work up made by hepatologist. This is very high ALT and the cause should be established. If the diagnosis cant be established by ultrasound and lab work then liver biopsy may be the option. Certain food and medications may lead to such dissarngement of findings.
I hope I have answered you query
Kindly regards. Wish you a good health.
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What Causes Elevated ALT Level?

Hi and welcome to Healthcaremagic. I understand your concerns. If viral hepatitis and alcoholic hepatitis are ruled out then there are several other conditions which could lead to ALT elevation. It includes autoimmine hepatitis and gilberts diseases and you need extended work up made by hepatologist. This is very high ALT and the cause should be established. If the diagnosis cant be established by ultrasound and lab work then liver biopsy may be the option. Certain food and medications may lead to such dissarngement of findings. I hope I have answered you query Kindly regards. Wish you a good health.