Hi there, Had question regarding Hepatitis B virus serology tests results. Wanted to confirm about Hepatitis B surface antigen result, as you can see course of the tests had been done started back from 2007 to 2017 this year, it has been confirmed that I am immunity to HBV indicated by hepatitis b surface antibodies. However, from 2007 to 2014 laboratory tests show that HBsAg was negative and this year 2017 had weak positive of 1.06 (cut off = 1.0) of HBsAg, therefore, confirmation test was done which showd 102% (anything above 50% considered to be positive) with negative HBV e antigen and HBV core antibody. From these results, I am aware that highly likely that I will not have HBV but why and what could be the possibility of HBsAg rising up after so many years? 17T0000      M 34 13Jun17 HBsAg EQUIVOCAL Anti HBs 14.3 mIU/mL - indicates immunity to HBV. Anti HCV : Negative No serological evidence of past or present Hepatitis C infection. HBV e antigen : Negative HBV Core antibody : Negative Low reactive HBsAg result of uncertain clinical significance. Please note results for anti-HBs performed on current and previous specimens collected from this patient indicate patient is immune to Hepatitis B. This comment was added by TH. HIV 1/2 Antibody/Antigen: Negative The HIV results were obtained using a 4th generation assay. This assay detects the presence of HIV p24 antigen and antibodies to HIV-1 and HIV-2. 14/0000 20Mar14 Sodium 141 mmol/L 135-145 Potassium 4.4 mmol/L 3.5-5.2 Creatinine 69 umol/L 60-105 eGFR 90 mL/min 60 .............LIVER FUNCTION TESTS................ Bilirubin total 18 umol/L 0-20 Alk phosphatase 102 U/L 40-110 GGT 73 U/L ***** 0-60 ALT 159 U/L ***** 0-50 AST 79 U/L ***** 0-40 Total protein 73 g/L 60-80 Albumin 40 g/L 33-48 Globulins 33 g/L 25-35 .............IRON STUDIES ........................ Iron 22 umol/L 10-30 Transferrin 2.76 g/L 2.00-3.60 Iron saturation 35 % 20-50 Ferritin Ferritin 320 ug/L ***** 30-300 CRP 3.5 mg/L 0-8 HAEMATOLOGY..... Ref.Range HAEMOGLOBIN 155 g/L 130-175 HCT 0.46 L/L 0.40-0.52 MCV 89 fL 80-99 MCH 30 pg 27-33 W.B.C. 7.1 x10^9/L 4.0-11.0 .............DIFFERENTIAL............................ Neut Seg 3.0 x10^9/L 1.9-7.5 Lymphocyte 2.9 x10^9/L 1.0-4.0 Monocyte 0.6 x10^9/L 0.2-1.0 Eosinophil 0.5 x10^9/L 0.0-0.5 Basophil 0.1 x10^9/L 0-0.2 PLATELET COUNT 193 x10^9/L 150-400 .............Hepatitis Serology................. HBsAg Negative Anti HBs 24.7 mIU/mL - indicates immunity to HBV. Anti HCV : Negative No serological evidence of past or present Hepatitis C infection. 09/0000 26May09 .............LIVER FUNCTION TESTS................ Bilirubin total 23 umol/L ***** 0-20 Alk phosphatase 82 U/L 40-110 GGT 70 U/L ***** 0-60 ALT 152 U/L ***** 0-50 AST 80 U/L ***** 0-40 Total protein 75 g/L 60-80 Albumin 44 g/L 33-48 Globulins 31 g/L 25-35 .............MID-STREAM URINE..................... AMENDED REPORT :- MICROSCOPY Leucocytes 0 x10^6/L Erythrocytes 0 x10^6/L Nitrite Negative Bacteria None seen Protein Nil Glucose Nil Bilirubin Nil Urobilinogen Normal pH 6.0 Ketones Nil Epithelial cells Small numbers CULTURE : No growth .............Hepatitis Serology................. HBsAg Negative Anti HBs 51.9 mIU/mL - indicates immunity to HBV. Anti HCV : Negative No serological evidence of past or present Hepatitis C infection. 07/0000 16Oct07 .............Hepatitis Serology................. HBsAg Negative HIV 1/2 Antibody/Antigen: Negative The HIV results were obtained using a 4th generation assay. This assay detects the presence of HIV p24 antigen and antibodies to HIV-1 and HIV-2. .............SYPHILIS SEROLOGY.................... AMENDED REPORT :- RPR Negative TPPA Negative