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What Causes Elevated TPR And Left Ventricular Hypertrophy?
Patient: 5â??6â??, 210 lb., 66-year-old male
History: BP was >180/115 on three separate days. Examination showed normal to low plasma rennin activity, elevated total peripheral resistance (TPR), cardiac output (CO) of 7.2 L/min, x-rays showed evidence of left ventricular hypertrophy, retinal hemorrhages, and mild polyuria. Recommended therapy was weight reduction to his ideal weight, a low salt diet (
What is the diagnosis for this individual?
History: BP was >180/115 on three separate days. Examination showed normal to low plasma rennin activity, elevated total peripheral resistance (TPR), cardiac output (CO) of 7.2 L/min, x-rays showed evidence of left ventricular hypertrophy, retinal hemorrhages, and mild polyuria. Recommended therapy was weight reduction to his ideal weight, a low salt diet (
What is the diagnosis for this individual?
Mon, 4 Jun 2018
Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.
Elevated TPR might be from an essential hypertension or secondary hypertension. Normal renin levels suggest that a secondary cause, like renal artery stenosis is excluded. Ventricular hypertrophy, retinal hemorrhage and proteinuria are caused from an untreated hypertension for a long time. I suggest you to do an ECG, a cardiac sonography, a 24 hour blood pressure monitor Holter, a renal sonography and some routine blood tests to see renal function. After doing this, you might need treatment for high blood pressure.
All the best!
Elevated TPR might be from an essential hypertension or secondary hypertension. Normal renin levels suggest that a secondary cause, like renal artery stenosis is excluded. Ventricular hypertrophy, retinal hemorrhage and proteinuria are caused from an untreated hypertension for a long time. I suggest you to do an ECG, a cardiac sonography, a 24 hour blood pressure monitor Holter, a renal sonography and some routine blood tests to see renal function. After doing this, you might need treatment for high blood pressure.
All the best!
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