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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Elevated Lipid In Blood While On Neurontin, Percocet And Zanaflex?

I am on pain management for severe back injuries and back surgeries from being a nurse. approx 8 months ago I had typical blood work done that included lipid panel and everything was with in norm limits. I just recently had blook draw again and trig. were 315!! I also had extemely elevated inflammatory such as sed rate etc. This in combination have caused me to have very high cardiac enzymes. I am taking neurontin, percocet, and zanaflex which is presribed by dr. Is is possible that any of these medications can cause such elevated lipids? I have not changed my diet and if anything I have actually been eating healthier. I can't seem to lose any weight and have frequent swelling of my stomach. HELP!!!
Thu, 30 Oct 2014
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Geriatrics Specialist,  's  Response
Hi,
Thanks for asking.
Based on your query, my opinion is as follows.
1. Triglycerides of 315 is very high. The medications neurontin, percocet and zanaflex can all affect liver. Particularly percocet can damage liver in high doses. This could be one of the cause of high triglycerides.
2. More common cause would be increased bad fat intake in diet. Medications alone cannot be the cause. You need to get into a low fat, low carbohydrate with moderate protein diet. Include lots of fiber to reduce triglycerides levels.
3. Zanaflex can affect cardiac enzymes levels. Not to worry. Its only short term. Weight reduction is essential along with medications like fibrates to reduce triglycerdies. Get on a diet along with moderate exercises to loose weight.
Hope it helps.
Any further queries, happy to help again.
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What Causes Elevated Lipid In Blood While On Neurontin, Percocet And Zanaflex?

Hi, Thanks for asking. Based on your query, my opinion is as follows. 1. Triglycerides of 315 is very high. The medications neurontin, percocet and zanaflex can all affect liver. Particularly percocet can damage liver in high doses. This could be one of the cause of high triglycerides. 2. More common cause would be increased bad fat intake in diet. Medications alone cannot be the cause. You need to get into a low fat, low carbohydrate with moderate protein diet. Include lots of fiber to reduce triglycerides levels. 3. Zanaflex can affect cardiac enzymes levels. Not to worry. Its only short term. Weight reduction is essential along with medications like fibrates to reduce triglycerdies. Get on a diet along with moderate exercises to loose weight. Hope it helps. Any further queries, happy to help again.