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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Elevation In Direct Bilirubin Levels Of An Infant?

Hi doctor, My son was born last January, 11th, after the forth day, we found that he has jaundice, we thought it is physiological, as Bilirubin was 2.5 (Direct) and 9 (Indirect) and he received photo-therapy for 3 nights, but afterwards we found that direct bilirubin became higher (~12.0) and indirect lowers (~4.0), he is diagnosed as Neonatal Hepatitis, mostly all his analyses OK (TORSCH only has 35 in Rubella IgG) and SGOT and SGPT slightly high than references. After taking medications (Multivitamins ABIDEC) and Ursogall syrup for 2 months, direct bilirubin lowers to 6 and indirect still to 4, after 2 weeks, direct bilirubin again became 15 and indirect is still 4. Plz. thankfully advise!
Thu, 27 Feb 2025
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Anesthesiologist 's  Response
Hello,

Neonatal hepatitis can be caused by infection, biliary atresia or defects in formation of bile ducts, alpha 1 antitrypsin deficiency, genetic, neoplastic, vascular toxic and immune causes, or idiopathic neonatal hepatitis. The treatment depends upon the cause of neonatal hepatitis.

If it is a surgical cause, early surgery prevents unnecessary complications. Please do consult a gastroenterology specialist for further evaluation and appropriate treatment by in person clinical examination.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Pallavi M., Anesthesiologist
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What Causes Elevation In Direct Bilirubin Levels Of An Infant?

Hello, Neonatal hepatitis can be caused by infection, biliary atresia or defects in formation of bile ducts, alpha 1 antitrypsin deficiency, genetic, neoplastic, vascular toxic and immune causes, or idiopathic neonatal hepatitis. The treatment depends upon the cause of neonatal hepatitis. If it is a surgical cause, early surgery prevents unnecessary complications. Please do consult a gastroenterology specialist for further evaluation and appropriate treatment by in person clinical examination. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Pallavi M., Anesthesiologist