Hi my name is sue. Have been on Premarin 0.625 for thirty years. Last two years am showing severe symtons. Fatigue, insomnia , massive ridges in my finger nails, nails brittle and flakey, headaches, nausea , skin extremely dry ,dry heals elbows. My weight is very difficult to control. I have stopped Premarin for three days now will I have side effects etc. reason on Premarin was hysterectomy at age 27years old am now 60years