I am 46 and have a thyroid hypoechoic nodule with central calcification measuring 0.5x0.5x0.4 with normal TSH. I have an inflammatory disease with no defined diagnose yet. I did have a blood result of neg. RA factor-T3 3.11 within normal range-negative ANA and c reactive-low blood count not significantly low-not -high globulin 3.70-normal send rate-ACCP 27.4 positive. My symptoms have been:freq. urination,constipation, stiffness & pain in feet, neck, knees, back,elbow and shoulders, fatigued all the time, depression-cry easily