Hello dear . Welcome to ask a doctor service. I read your question and here is my advice. The best advice when it comes to caffeine seems to be – keep your caffeine intake low, and constant. Don’t have a litre of cola one day, none the next, and a can the nextIt’s not unusual for a soft drink to contain the equivalent of 1/4 cup of sugar. That’s a lot of sugar, and it won’t break down slowly. That means sugar spikes. That alone could trigger an attack. There could also be a cumulative effect (too much sugar over and over for several days). There’s also a more complex relationship with glucose, insulin, and nitric oxide. The longer term issues could include things like diabetes and obesity, both closely related to migraine Take care. Hope I have answered the question. Let me know if I can assist you further. Best regards,