I am frequently woken in the early morning hours with mild to severe headache. The only effective relief is to sit upright in a chair for an hour or more- not the ideal cure at 3am on a winters morning! Panadol and other so-called headache cures have absolutely no effect. In desparation Tramadol gives some relief but unpleasant after effects and is not for regular use. I am 83 y/o and apart from the headaches in very good health, drink little alcohol,have tried Physio for neck manipulation, purchased an expensive mattress and pillow and discussed with GP many times but the problem continues! Would appreciate any suggestions Thankyou Vince