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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Higher Value Of ALP In Blood Test?

Hi,
Fasting lab my T-Bili was 2.1 all other liver enzymes normal. Recheck with a non fasting lab, my T-Bili was 1.7, however, T-ALKP went up to 131. I had two non-fasting labs same results T-ALKP 131 and T-Bili 1.6. Now Dr suggest a ultrasound. Not sure if I should go this route or try another fasting lab. I'm 53 year old female also going thru menopause.
Fri, 27 Jan 2017
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General Surgeon 's  Response
The alkaline phosphatase test (ALP) is used to help detect liver disease or bone disorders.

In conditions affecting the liver, damaged liver cells release increased amounts of ALP into the blood. This test is often used to detect blocked bile ducts because ALP is especially high in the edges of cells that join to form bile ducts. If one or more of them are obstructed, for example by a tumor, then blood levels of ALP will often be high.
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What Causes Higher Value Of ALP In Blood Test?

The alkaline phosphatase test (ALP) is used to help detect liver disease or bone disorders. In conditions affecting the liver, damaged liver cells release increased amounts of ALP into the blood. This test is often used to detect blocked bile ducts because ALP is especially high in the edges of cells that join to form bile ducts. If one or more of them are obstructed, for example by a tumor, then blood levels of ALP will often be high.