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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Hives And Upper Abdominal Pain While On Hydroxychloroquine?

I have recently (June 2015) been diagnosed with Myopathic dermatomyositis. In July I was prescribed Hydroxychloroquine. I have not seen any improvement and 4 days ago, I developed occasional sharp pain in the upper abdomen and through to the upper back. They come and go. At about the same time I developed hives that almost cover my body. Antihistamines have worked for a few hours but I am having to take them much too frequently. My whole body seems to be off kilter. I have stopped the medication until I can talk to my doctor. I am miserable.
Wed, 30 Sep 2015
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General & Family Physician 's  Response
Hi
I can understand your concern.

Drug eruptions to Hydroxychloroquine.

After having gone through your history it seems to me you have developed an allergic reaction to Hydroxychloroquine apparently prescribed to treat myopathic dermatomyositis.

I would suggest you to continue to take oral antihistamines or a topical steroid till you consult your treating rheumatologist.
You may need oral steroids like Prednisone or Immunosuppressive (steroid-sparing) agents for the treatment of myopathic dermatomyositis.

Meanwhile avoid sun exposure and use sunscreens & photoprotective clothing.

Hope the suggestion given above could be useful in getting the treatment.
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What Causes Hives And Upper Abdominal Pain While On Hydroxychloroquine?

Hi I can understand your concern. Drug eruptions to Hydroxychloroquine. After having gone through your history it seems to me you have developed an allergic reaction to Hydroxychloroquine apparently prescribed to treat myopathic dermatomyositis. I would suggest you to continue to take oral antihistamines or a topical steroid till you consult your treating rheumatologist. You may need oral steroids like Prednisone or Immunosuppressive (steroid-sparing) agents for the treatment of myopathic dermatomyositis. Meanwhile avoid sun exposure and use sunscreens & photoprotective clothing. Hope the suggestion given above could be useful in getting the treatment.