I have been taking Cymbalta for osteoarthritis, swelling, chronic pain, etc... It is causing terrible hives/rash however it works really good for all of my symptoms. I am looking for a good alternative without skin rash/hives side affects. I have had multiple knee surgeries, rt knee replacement, rt shoulder repair, shingles multiple times even after vaccine, Rocky Mtn spotted fever, staff infection on my skin rashes, h pylori. I still work and I am an active 45 year old female (complete hysterectomy). I need something to reduce pain & swelling, help with skin and stress & anxiety. (No real depression other than the pain & diminished quality of life due to symptoms.