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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Increased Level Of Valium In Drug Urine Test?

My monthly drug screen showed twice the amount of prescribed valium in my urine...when I didn t take more than prescribed...I take oxycodone 7.5 mgs q 6 hrs for pain...I never take more than prescribed....either of them. WHAT could cause the false high amount of valium in my urine...I ve been told liver disease causes the valium not to be metabolized...please help me find a reason for this high valium content because I don t take more than prescribed and my pain management dr.is suspicious of abuse...I drink lemon water all the time...could that be a problem? And I had started taking Nitrofurantoin mcr 50 mg.daily...I was detoxing from Paxil 40 mg/day after 10 years of use...but didn t use more valium. I am desperate to find out WHY the LG amt was found in my urine results. Please help me???? I also take Celecoxib 200 mg BID...thanks for your help... YYYY@YYYY
Tue, 31 Mar 2020
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General Surgeon,  's  Response
Hello,

* It is the chronic consumption of Paxil 40 mg , which is selective serotonin reuptake inhibitor which has affected drug metabolism pathway at P 450 levels of the liver, which is showing up increased metabolism of the drug Valium.

* It is the underlying effect of high level of active metabolites of the drug showing such urine test result.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr. Bhagyesh V. Patel
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What Causes Increased Level Of Valium In Drug Urine Test?

Hello, * It is the chronic consumption of Paxil 40 mg , which is selective serotonin reuptake inhibitor which has affected drug metabolism pathway at P 450 levels of the liver, which is showing up increased metabolism of the drug Valium. * It is the underlying effect of high level of active metabolites of the drug showing such urine test result. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr. Bhagyesh V. Patel